MiRNA-based Lifespan extension therapy: MiRNA-380-5p mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 4/June/2014, 7.53 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., MiRNA-based Lifespan extension therapy: MiRNA-380-5p increases mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 4/June/2014, 7.53 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: It has been shown earlier that angiotensin II type I […]

MiRNA-based therapy for Human Cancer: MiRNA-195 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 3/June/2015, 11.05 am

The 1989 Noble prize winner in Chemistry, Prof. Thomas R. Cech, from the University of Colorado BioFrontiers Institute, USA, has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic insights into how TPP1 regulates telomerase function. In connection with this finding, Dr Boominathan, Founder Director-cum-chief scientist […]

Anti-viral therapy: Menin (MEN1) suppresses porcine reproductive and respiratory syndrome virus infection via up regulation of its target gene, 3/June/2015, 10.53 am

A study from the Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing 100193, China; and CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China shows that “Cellular microRNA miR-26a suppresses replication of […]

Molecular Cancer therapy:Resistin inhibits cancer cell proliferation via down regulation of proto-oncogene c-Jun and its target genes, 3/June/2014, 10.33 pm

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Molecular Cancer therapy: Resistin inhibits cancer cell proliferation via down regulation of proto-oncogene c-Jun and its target genes, 3/June/2014, 10.33 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: It has been shown earlier that c-Jun and its target […]

Interleukin-based Lifespan extension therapy: IL-17 prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 3/June/2014, 10.23 pm

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Interleukin-based Lifespan extension therapy: IL-17 prolongs  mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 3/June/2014, 10.23 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: It has been shown earlier that angiotensin II type I receptor […]

Natural product-based therapy for T2DM: Grape skin ethanol extract (GSE) enhances insulin secretion by increasing glucagon-like peptide-1 secretion via up regulation of its target gene, 3/June/2015, 10.19 pm

A study from the Clinic for Endocrinology, Diabetes & Metabolism and Department Biomedicine, University Hospital Basel, Basel, Switzerland shows that “Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.” This study was published in the 30 October  2011 issue of the journal “Nature Medicine” [the number 1 journal in General Medicine with an I.F of 24.973] by Prof. Donath MY, Ellingsgaard H and […]