Natural product-based weight loss therapy: Berberine decreases food intake and body weight via up regulation of its target gene, 25/May/2015, 23.57
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based weight loss therapy: Berberine decreases food intake and body weight via up regulation of its target gene, 25/May/2015, 23.57, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: This study suggests, for the first time, that Berberine, by increasing the […]
Small molecule-based therapy for DM: Icariin, a phosphodiestrase-5 inhibitor, lowers hepatic glucose production and plasma glucose levels via up regulation of its target gene, 25/May/2015, 23.53
A recent study from the [1] Toronto General Research Institute and Department of Medicine, Toronto, Ontario, Canada, [2] Department of Physiology, University of Toronto, Toronto, Ontario, Canada, [3] Department of Medicine, University of Toronto, Toronto, Ontario, Canada, and [4] Banting and Best Diabetes Centre, University of Toronto, Toronto, Ontario, Canada shows that “Metformin activates a duodenal Ampk-dependent pathway […]
MiRNA-based Diabetes mellitus therapy: Menin inhibits obesity-induced insulin resistance, glucose tolerance and lipid accumulation via up regulation of its target gene MiRNA-26a, 25/May/2015, 23.28
A study from the Division of Molecular Diabetes Research, Department of Diabetes and Metabolic Diseases, City of Hope National Medical Center, Duarte, California, USA shows that “MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids.” This study was published in the 11 May 2015 issue of the Journal “Journal of Clinical Investigation” (one of the best journal in Clinical […]
Molecular therapy for Metastatic Pancreatic/intestine/ovarian Cancers: GATA3 suppresses the expression of PDGF Receptor β (PDGFRβ) via down regulation of its target gene, 25/May/2015, 21.17
A study from Watson School of Biological Sciences shows that Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling. This study was published in the April 10, 2014 Cell by Prof. Dr Scott Lowe, Watson School of Biological Sciences, CSHL, New York; Prof. Dr Carol Prives, Department of Biological Sciences, Columbia University, New York; and others. On the foundation of this interesting finding, Dr […]
Natural product-based Lifespan extension therapy: Agaricus blazei Murill (AbM), a medicinal mushroom, extends life span by down regulating the expression of Insulin receptor substrate-2, 25/May/2015, 19.44
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based Lifespan extension therapy: Agaricus blazei Murill (AbM), a medicinal mushroom, extends life span by down regulating the expression of Insulin receptor substrate-2, 25/May/2015, 19.43, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: This study suggests, for the first time, […]
Lifespan extension therapy: E2F1 increases life span via up regulation of its target gene BubR1, 25/May/2015, 18.26
A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School of Medicine, The University of New South Wales, Australia shows that Sirtuin-2 induces the checkpoint kinase BubR1 to increase lifespan. This study was published in the 1 July 2014 issue of the journal “EMBO” by Prof Sinclair, North BJ, and others. […]