Natural product-based therapy for mitigating human preterm birth: Dioxinodehydroeckol, isolated from Ecklonia cava, inhibits preterm birth via down regulation of its target gene, 23/May/2015, 23.37

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based therapy for mitigating human preterm birth: Dioxinodehydroeckol, isolated from Ecklonia cava, inhibits preterm birth via down regulation of its target gene, 23/May/2015, 23.37, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance:  This suggests, for the first time, that Dioxinodehydroeckol, by increasing the expression of its target gene, it may inhibit preterm birth.  Thus, pharmacological […]

Molecular therapy for Metastatic human tumors: Ndfip1 inhibits cellular proliferation, invasion and metastasis by decreasing the expression of tumor suppressor Interleukin-1β (IL1-β) via down regulation of its target gene, 22/May/2015, 23.28

A study from the Cell Pathology Division, The Children’s Hospital of Philadelphia, Philadelphia, USA shows that “TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production during iTreg cell differentiation.” This study was published in the 15 November  2009 issue of the journal “Nature Immunology” [the number 1 journal in Immunology with an I.F of 24.973] by Prof. Oliver PM, Beal and others. On the […]

Natural product-based therapy for pulmonary arterial hypertension: Fisetin, a flavonoid enriched in strawberries, Mangoes and Cucumber, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 23/May/2015, 23.22

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in General Medicine with an I.F of 28.054] by Prof. Thistlethwaite PA, Li X and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-based therapy for pulmonary arterial hypertension: Fisetin, […]

Natural product-based High-Density lipoprotein therapy: Root extract of Atractylodes japonica Koidzumi increases High-Density lipoprotein levels via up regulation of ABCA1, 23/May/2015, 14.26

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based High-Density lipoprotein therapy: Root extract of Atractylodes japonica Koidzumi increases High-Density lipoprotein levels via up regulation of ABCA1, 23/May/2015, 14.25, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance:  This suggests, for the first time, that Root extract of Atractylodes japonica Koidzumi, by increasing the expression of its target gene ABCA1, it […]

Regenerative Stem cell therapy for Myocardial Infarction: Dehydroabietic acid (DAA) improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 23/May/2015, 14.14

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Regenerative Stem cell therapy for Myocardial Infarction: Dehydroabietic acid (DAA) improves myocardial function after myocardial infarction via  up regulation of […]

Natural product-based Growth hormone therapy: Oleanolic acid, one of the major constituent of Tulsi, increases the expression of Growth hormone (GH) via down regulation of its target gene, 23/May/2015, 14.10

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based Growth hormone therapy: Oleanolic acid, one of the major constituent of Tulsi, increases the expression of Growth hormone (GH) via down regulation of its target gene, 23/May/2015, 14.10, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance:  This suggests, for the first time, that Oleanolic acid, by decreasing the expression of its target gene, […]