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January 18, 2017

Vitamin-E-based therapy for glucose homeostasis and TIIDM: α-Tocopherol, a form of Vitamin-E found in Almonds, Sunflower seeds, and Tomato among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 18/January/2017, 7.00 am

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
January 17, 2017

Natural product-derived therapy for enhancing anti-cancer immunity: Indole-3-carbinol (I3C), found in Broccoli, cabbage, cauliflower, brussels sprouts, collard greens and kale among others, decreases the level of LATS1/2 (large tumor suppressor 1 and 2), increases immunogenicity of tumors, enhances anti-tumor immune responses, and inhibits tumor growth via down regulation of its target gene, 17/January/2017, 11.58 pm

Introduction: What they say:  A study from the Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA shows that […]
January 17, 2017

Small molecule-based PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: Unacylated ghrelin (UnAG) inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 17/January/2017, 11.35 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
January 17, 2017

Natural product-derived PD-1 pathway blockade for Human cancer therapy: Baicalein, isolated from Scutellaria Baicalensis/Lateriflora and Oroxylum indicum among others, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 17/January/2017, 11.17 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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