Small molecule-based Lifespan extension therapy: Ying Yang1 (YY1) extends mammalian life span via up regulation of its target gene BubR1, 16/May/2015, 17.33

A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School of Medicine, The University of New South Wales, Australia shows that Sirtuin-2 induces the checkpoint kinase BubR1 to increase lifespan. This study was published in the 1 July  2014 issue of the journal  “EMBO” by Prof David Andrew Sinclair, North […]

Natural product-based Growth hormone therapy: 6-Gingerol, a pungent component of Ginger, increases the expression of Growth hormone (GH) via down regulation of its target gene, 16/May/2015, 17.57

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based Growth hormone therapy: 6-Gingerol, a pungent component of Ginger, increases the expression of Growth hormone (GH) via down regulation of its target gene, 16/May/2015, 17.57, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance:  This suggests, for the first time, that 6-Gingerol, by decreasing the expression of its target gene, it may increase the […]

Vitamin-based therapy for T2DM & lifespan extension: α-Tocopherol increases UCP protein expression, energy expenditure, glucose tolerance, insulin sensitivity, cold exposure tolerance and extends lifespan via up regulation of its target gene, 16/May/2015, 13.28

A study from the Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Diabetes Unit, Medical Services, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; European Molecular Biology Laboratory, Mouse Biology Unit, 00015-Monterotondo, Italy; and Department of Pharmacology, University of Oxford, Oxford OX1 3QT, […]

Regenerating the lost cardiomyocytes in Myocardial patients: Pear extract increases the expression of ERBB2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 16/May/2014, 10.48 am

A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published in the 6 April  2015 issue of the journal “Nature cell biology” (the number 1 journal in “Cell biology” research with an impact factor of 20.761) by Prof Tzahor E, D’Uva G, and others. […]

Natural product-based therapy for T2DM: Withaferin A, a natural compound isolated from Withania somnifera, enhances insulin secretion by increasing glucagon-like peptide-1 secretion via up regulation of its target gene, 16/May/2015, 10.41 am

A study from the Clinic for Endocrinology, Diabetes & Metabolism and Department Biomedicine, University Hospital Basel, Basel, Switzerland shows that “Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.” This study was published in the 30 October  2011 issue of the journal “Nature Medicine” [the number 1 journal in General Medicine with an I.F of 24.973] by Prof. Donath MY, Ellingsgaard H and […]

MiRNA-based Lifespan extension therapy: MiRNA-208 inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 16/May/2015, 10.38 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., MiRNA-based Lifespan extension therapy: MiRNA-208 inhibits senescence and  extends life span by down regulating the expression of  adenylate cyclase 5 (ADCY5), 16/May/2015, 10.38 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: This study suggests, for the first time, that MiRNA-208 may extend the […]