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April 16, 2017

Natural product-derived therapy for Metastatic cancers: Cucurbitacin E, found in Watermelons, Cubeb pepper and Oregano among others, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 16/April/2017, 11.59 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
April 16, 2017

MiRNA-based antiviral therapy against Neuroinvasive West Nile virus: MiR-660 increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 16/April/2017, 11.53 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University […]
April 16, 2017

Natural product-derived therapy for tuberculosis: Persimmon tannin extract (PTE), found abundantly in cotton cheese and Granola among others, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 16/April/2017, 11.45 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
April 15, 2017

Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Ampelopsin [AMP; also called dihydromyricetin (DHM)], a flavonoid mainly found in Ampelopsis grossedentata (commonly known as Mayeam), increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 15/April/2017, 11.36 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]
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