Immune enhancement therapy: Follicule stimulating hormone (FSH) increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 7/May/2015, 15.30
A recent study from the Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection.” This study was published in the 2 March 2015 issue of the Journal “Nature Immunology” [I.F: 24.973] by Drs. Zusen Fan, Xia and others. On the […]
Steroid-based neuropathic pain relieving therapy: Testosterone inhibits neuropathic pain via down regulation of T cell–derived leukocyte elastase, 7/May/2015, 15.25
A recent study from the Pharmacology Institute, University of Heidelberg, Heidelberg, Germany; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA shows that the Serine protease inhibitor-A3N attenuates neuropathic pain by inhibiting T cell–derived leukocyte elastase. This study was published in the 27 April 2015 issue of the Journal “Nature Medicine” (the no.1 journal in General medicine with an impact factor of >28) by Prof.Dr. Kuner, Vicuna and […]
Small molecule-based therapy for p53-deficient tumors: PAPD5 suppresses & increases the expression of DNp63α & IAPP (Amylin), respectively, and induces regression of p53-mutated human tumors via down regulation of its target gene, 7/May/2015, 14.40
A recent study from the Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [2] Department of Translational Molecular Pathology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [3] Graduate School of Biomedical Sciences, The University of […]
Natural product-based therapy for T2DM: Onion peel extract (OPE) enhances insulin secretion by increasing glucagon-like peptide-1 secretion via up regulation of its target gene, 7/May/2015, 14.21
A study from the Clinic for Endocrinology, Diabetes & Metabolism and Department Biomedicine, University Hospital Basel, Basel, Switzerland shows that “Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.” This study was published in the 30 October 2011 issue of the journal “Nature Medicine” [the number 1 journal in General Medicine with an I.F of 24.973] by Prof. Donath MY, Ellingsgaard H and […]
Sunlight exposure not only ameliorates T2DM but also extends lifespan: Cholecalciferol increases UCP protein expression, energy expenditure, glucose tolerance, insulin sensitivity and extends lifespan via down regulation of its target gene, 7/May/2015, 08.35 am
A study from the Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Diabetes Unit, Medical Services, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; European Molecular Biology Laboratory, Mouse Biology Unit, 00015-Monterotondo, Italy; Department of Pharmacology, University of Oxford, Oxford OX1 3QT, UK […]
Regenerating the lost cardiomyocytes in Myocardial patients: ARID3B increases the expression of ERBB2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 7/May/2014, 8.24 am
A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published in the 6 April 2015 issue of the journal “Nature cell biology” (the number 1 journal in “Cell biology” research with an impact factor of 20.761) by Prof Tzahor E, D’Uva G, and others. […]