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March 12, 2017

Natural product-derived combination therapy for Hepatocellular carcinoma: A therapeutic mix encompassing Hyperoside and Quercetin, isolated from Drosera rotundifolia, and Levisticum officinale, respectively, attenuates phosphoenolpyruvate carboxykinase (PEPCK1) sumoylation, stabilizes PEPCK1 levels, promotes gluconeogenesis, inhibits glycolysis and attenuates the progression of hepatocellular carcinoma via up regulation of its target gene, 12/March/2017, 11.16 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
March 11, 2017

Natural product-derived therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Hyperoside, isolated from Droser rotundifolia, of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 11/March/2017, 11.11 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]
March 11, 2017

Natural product-derived therapy for Metastatic cancers: Kaempherol, one of the main components of Aloe vera, decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 11/March/2017, 6.27 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 10, 2017

Vitamin-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Folic acid promotes an insulin-sensitized state via up-regulation of its target gene Lin-28, 10/March/2017, 10.53 pm

What we say:  Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Vitamin-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Folic acid promotes an insulin-sensitized state via up-regulation […]
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