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March 4, 2017
Published by admin_auro at March 4, 2017
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Natural product-based therapy for Metastatic cancers: Hyperoside, isolated from Drosera rotundifolia, and Common self-heal, among others, increases the expression of BTG2 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 4/March/2017, 7.35 am

Research findings to Therapeutic opportunity:  A number of studies suggest that Hyperoside functions as an anticancer agent. However, the mechanism of action is far from clear. […]
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March 4, 2017
Published by admin_auro at March 4, 2017
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Molecular therapy for Metastatic cancers: α-Solanine, isolated from Flowers and Fruits of bittersweet nightshade, decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 4/March/2017, 7.21 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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March 3, 2017
Published by admin_auro at March 3, 2017
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Natural product-derived antiviral therapy for HIV virus: Epigallocatechin gallate, one of the main components of Green tea, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 3/March/2017, 11.11 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
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March 3, 2017
Published by admin_auro at March 3, 2017
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Natural product-derived therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Naringenin, isolated from Grapefruit, decreases the expression of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 3/March/2017, 10.53 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]
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