Regenerative therapy for DM: MiRNA-181c increases insulin-secreting cell mass and function via down regulation of its target genes, 9/April/2015, 08.58 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Regenerative therapy for DM: MiRNA-181c increases insulin-secreting cell mass and function via down regulation of its target genes, 9/April/2015, 08.59 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that MiRNA-181c, by decreasing the expression of its target gene, it may increase insulin-secreting cell mass and function. Thereby, it may increase the insulin […]

Regenerative Stem cell therapy for Myocardial Infarction: Twist, an inducer of Epithelial to Mesenchymal transition, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 08/March/2015, 08.31 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Regenerative Stem cell therapy for Myocardial Infarction: Twist, an inducer of Epithelial to Mesenchymal transition, improves myocardial function […]

Molecular therapy for Myeloid leukemia: GATA3 increases the expression of tumor suppressor protein SPRY4 via down regulation of its target gene, 9/April/2015, 08.27 am

A study from the Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA; and Howard Hughes Medical Institute, New York, New York, USA  shows that “Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.” This study was published in the 30 March  2015 issue of the Journal “Nature Genetics” (the no.1 journal in Genetics with […]

Small molecule-based Life-span extension therapy: 5-aminoimidazole-4-carboxamide riboside (AICAR), an analog of AMP, inhibits senescence and extends lifespan by up regulating the expression of longevity gene Sirtuin-1, 8/April/2015, 23.51

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Small molecule-based Life-span extension therapy: 5-aminoimidazole-4-carboxamide riboside (AICAR), an analog of AMP, inhibits senescence and  extends lifespan by up regulating the expression of  longevity gene Sirtuin-1, 8/April/2015, 23.51, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: This study suggests, for the first […]

Treating regional enteritis disease with an anticancer drug: Campothecin (CPT) increases the expression of immunosuppressive cytokine TGF-β1 and inhibits the progression of regional enteritis disease via up regulation of its target gene, 8/April/2015, 23.41

A recent study from the Department of Systems Medicine, University of Tor Vergata, Italy shows that Mongersen, an oral SMAD7 antisense oligonucleotide, inhibits regional enteritis disease. This study was published in the 19 March 2015 issue of of the Journal “N. Engl. J. Med.” [I.F: 54.42]  by Prof Pallone F., Monteleone G, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief […]

Regenerative Stem cell therapy for Myocardial Infarction: MiRNA-10a/b improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 08/March/2015, 23.25

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Regenerative Stem cell therapy for Myocardial Infarction: MiRNA-10a/b improves myocardial function after myocardial infarction via  up regulation of PNUTS/PPP1R10 […]