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February 11, 2017

Anti-telomerase cancer therapy: Calycosin, the major bioactive isoflavonoid in the dry root extract of Radix astragali, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 11/February/2017, 5.58 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
February 10, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Rice bran protein hydrolysates (RBPs) increase Pax6 and insulin expression, decrease the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improve insulin sensitivity, promote glucose homeostasis and prevents progression to TIIDM via down regulation of their target gene, 10/February/2017, 11.22 pm

Introduction: What they say  A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
February 10, 2017

Natural product-derived therapy for Metastatic human tumors: Magnolin, one of the main components of herb Magnolia fargesii/Flos, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 10/February/2017, 10.55 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
February 10, 2017

Small molecule-based PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: BMP4 (Bone Morphogenetic Protein-4) inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 10/February/2017, 9.52 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
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