T2DM drugs function as anti-metastatic agents: Acarbose, the widley used drug in the treatment of T2DM, suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 26/March/2015, 23.57

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., T2DM drugs function as anti-metastatic agents: Acarbose, the widley used drug in the treatment of T2DM, suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 26/March/2015, 23.57, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: […]

Anti-metastasis therapy: BMP4 inhibits invasion and metastasis by altering protein trafficking via up regulation of tumor suppressor PTPN14 (Pez), 26/March/2015, 23.39

A recent study from the From the Centre for Cancer Biology, an Alliance between SA Pathology and University of South Australia, Adelaide, South Australia 5000, Australia. Discipline of Biochemistry, School of Molecular and Biomedical Science, The University of Adelaide, Adelaide, South Australia 5005, Australia. Department of Medicine, The University of Adelaide, Adelaide, South Australia 5005, Australia shows that “The […]

Molecular therapy for Myocardial ischemia after myocardial infarction: Proto-oncogene c-Myc inhibits cardiac ischemia via up regulation of Aldehyde dehydrogenase 2 (ALDH2), 26/March/2015, 22.48

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Molecular therapy for Myocardial ischemia after myocardial infarction: Proto-oncogene c-Myc inhibits cardiac ischemia via up regulation of Aldehyde dehydrogenase 2 (ALDH2), 26/March/2015, 22.49, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: The study presented here suggests that c-Myc, by decreasing the expression of its target genes, it may increase the expression of Aldehyde […]

MiRNA-based therapy for pulmonary hypertension: RKIP stifles pulmonary hypertension via down regulation of its target gene, 26/March/2015, 22.29

A recent study from the From the Department of Surgery, University of Pittsburgh Cancer Institute, Division of Pediatric Surgery, Children’s Hospital Pittsburgh, Department of Pharmacology and Chemical Biology, and Vascular Medicine Institute, University of Pittsburgh School of Medicine, PA, USA shows that “Genetic deletion of toll-like receptor 4 on platelets attenuates experimental pulmonary hypertension.” This study was published […]

Natural product-based therapy for Stress-induced heart failure: Oleic acid (OA), the major component of Neem Oil, protects against stress-induced heart failure via up regulation of SNX13, 26/March/2015, 10.48 am

A recent study from the Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai 200120, China shows that “SNX13 reduction mediates heart failure through degradative sorting of apoptosis repressor with caspase recruitment domain.” This study was published in the 8 October issue of 2014 Online journal “Nature Communications” by Prof Chen YH, Li […]

Drinking green tea will make you live longer: Epigallocatechin gallate (EGCG), the major component of green tea, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 26/March/2015, 10.41 am

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published in the 2 October 2009 issue of the Journal “Science” (I.F: 31.477 )by Prof Dominic J. Withers, Dr. Selman C and others. On the foundation of […]