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December 10, 2016

Natural product-derived therapy for overcoming chemoresistance in Human cancers: Amla extract increases the expression of CADM1, decreases BMI1 translocation, increases tumor suppressor INK4a/p16 expression and restores chemosensitivity in drug-resistant Human cancers via down regulation of its target gene, 10/December/2016, 8.51 am

What is known? I have published earlier that Amla extract: (i) increases the levels of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, […]
December 9, 2016

Natural product-derived therapy for brain repair and Lifespan extension: Dehydroleucodine, a Sesquiterpene Lactone from Gynoxys verrucosa and Artemisia douglassiana Besser, increases VGF and BDNF expression, promotes Oligodendrocytes (OP) proliferation, triggers myelination on neurons, reverts neural damage, produces antidepressant like effects, and prolongs lifespan via up-regulation of its target gene, 9/December/2016, 10.34 pm

What they say: Introduction:   A recent study from the Department of Biochemistry & Molecular Pharmacology, Smilow Research Center, Howard Hughes Medical Institute, NYU School of […]
December 9, 2016

Natural product-derived therapy for overcoming chemoresistance in Human cancers: Rhamnetin, found in cloves, increases the expression of CADM1, decreases BMI1 translocation, increases tumor suppressor INK4a/p16 expression and restores chemosensitivity in drug-resistant Human cancers via down regulation of its target gene, 9/December/2016, 10.07 pm

From Research findings to Therapeutic opportunity:  The study presented here suggests that Rhamnetin, by increasing the expression of its target genes, it may: (i) increase the expression of CADM1; […]
December 9, 2016

Natural product-derived Lifespan extension therapy: 2,4,5-trihydroxybenzaldehyde (TDB), found in Geum japonicum and Polygonum cuspidatum (PC), also known as Japanese knotweed, increases life span via up-regulation of its target gene BubR1, 09/December/2016, 11.56 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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