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December 6, 2016

MiRNA-based PD-1 pathway blockade for Human cancer therapy: MiR-940 decreases the expression of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 6/December/2016, 12.46 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
December 5, 2016

Natural product-based Lifespan extension therapy: Apple extract increases the expression of longevity-promoting and antiaging gene Klotho via up regulation of its target gene, 5/December/2016, 11. 33 pm

What is known? It has been shown earlier that Klotho: (1) extends the lifespan of mice by about 19-31%; and (2) increases cognition.  From Significance of […]
December 5, 2016

Natural product-derived therapy for brain repair and Lifespan extension: Shikonin, found in Zicao (also known as purple gromwell), increases VGF and BDNF expression, promotes Oligodendrocytes (OP) proliferation, triggers myelination on neurons, reverts neural damage, produces antidepressant like effects, and prolongs lifespan via up-regulation of its target gene, 5/December/2016, 10.52 pm

What they say: Introduction:   A recent study from the Department of Biochemistry & Molecular Pharmacology, Smilow Research Center, Howard Hughes Medical Institute, NYU School of […]
December 5, 2016

Natural product Lifespan extension therapy: Areca nut extract or Arecoline increases life span via up-regulation of its target gene BubR1, 05/December/2016, 10.10 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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