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December 2, 2016

Natural product-derived cardioprotective therapy: 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside, the main component of Polygonum multiflorum thunb, increases Spermidine levels, augments autophagy, mitophagy and mitochondrial respiration, lowers systemic blood pressure, protects it from cardiac diseases and promotes longevity via down regulation of its target gene, 2/December/2016, 7.31 pm

Introduction: What they say A study from the Institute of Molecular Biosciences, University of Graz, Humboldtstraße 50, A-8010 Graz shows that “Cardioprotection and lifespan extension by […]
December 2, 2016

Natural product-derived anti-ageing therapy: Shikonin, the major component of Zicao (also known as purple gromwell, the dried root of Lithospermum erythrorhizon), activates autophagy and extend lifespan via up regulation of its target gene, 2/December/2016, 7.14 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that: Shikonin, the major component of Zicao (also known as purple gromwell, the dried root […]
December 2, 2016

Natural product-derived therapy for triple-negative breast tumors: Withaferin A, isolated from Withania somnifera/Ashwagandha and Acnistus arborescens among others, increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 2/December/2015, 6.32 pm

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]
December 2, 2016

Natural product-derived therapy for Myocardial Infarction: Emodin (6-methyl-1,3,8-trihydroxy anthraquinone), found in Polygonum multiflorum, and Japanese knotweed among others, inhibits DNA damage responses, and telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 2/December/2016, 12.15 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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