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October 20, 2016

Natural product Antisepsis therapy: Epigallocatechin gallate, one of the components in green tea, increases Sestrin2 expression, inhibits NLRP3 inflammasome activation, and pro-inflammatory cytokines secretion, induces mitophagy in macrophages, and clears damaged mitochondria via autophagic machinery, and protects the host from sepsis via up- regulation of its target gene, 20/October/2016, 10.05 pm

A recent study from the Yonsei University College of Medicine, Seoul, Korea shows that Sestrin2 suppresses Sepsis by inducing mitophagy and inhibiting NLRP3 activation. This study […]
October 20, 2016

Natural product therapy targeting aberrant Lipid synthesis in Human cancers: Withaferin A, isolated from Withania somnifera (Ashwagandha), suppresses the expression of the principal enzyme in lipid synthesis, ACLY, inhibits aberrant lipid production, and tumor progression via up regulation of its target gene, 20/October/2016, 8.54 pm

A recent study from Rutgers Cancer Institute of New Jersey, Rutgers University, The State University of New Jersey, New Brunswick, New Jersey, USA shows that “Cullin3–KLHL25 ubiquitin […]
October 20, 2016

Natural product Immune enhancement therapy: Stinging nettle extract increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 20/October/2016, 7.57 am

A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity […]
October 20, 2016

Molecular therapy for Myocardial dysfunction: MiR-195 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial dysfunction via down-regulation of its target gene, 20/October/2016, 6.01 am

Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that: Molecular therapy for Myocardial dysfunction: MiR-195 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in […]
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