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December 24, 2016
Published by admin_auro at December 24, 2016
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Molecular therapy for Myocardial Infarction: KGF inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 24/December/2016, 11.35 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 24, 2016
Published by admin_auro at December 24, 2016
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Natural product-derived regenerative therapy for improving muscle repair and strength in the elderly: α-Lipoic acid, found in Brussels, broccoli, rice bran and among others, decreases the expression of HOXA9, increases skeletal muscle regeneration and imporves muscle stem cells function and repair via up regulation of its target genes, 24/December/2016, 11.14 pm

Introduction: What they say A study from Faculty of Medicine, Friedrich-Schiller-University, Germany shows that “Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.” This […]
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December 24, 2016
Published by admin_auro at December 24, 2016
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Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: γ-Bisabolene, one of the components in Cardamom, Cubeb, lemon, and Oregano among others, inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 24/December/2016, 10.45 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
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December 24, 2016
Published by admin_auro at December 24, 2016
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Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Cancer Suppressor BMP4 increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 24/December/2016, 9.36 pm

From Significance of the study to Public health relevance: Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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