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December 18, 2016
Published by admin_auro at December 18, 2016
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Natural product-derived therapy for overcoming chemoresistance in Human cancers: Honokiol increases the expression of CADM1, decreases BMI1 translocation, increases tumor suppressor INK4a/p16 expression and restores chemosensitivity in drug-resistant Human cancers via down regulation of its target gene, 18/December/2016, 11.01 pm

From Research findings to Therapeutic opportunity:  The study presented here suggests that Honokiol, by increasing the expression of its target genes, it may: (i) increase the expression of CADM1; […]
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December 18, 2016
Published by admin_auro at December 18, 2016
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Immune enhancement therapy: Annexin A2 (Anxa2) increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 18/December/2016, 10.52 pm

Introduction: What they say:  A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils […]
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December 18, 2016
Published by admin_auro at December 18, 2016
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Molecular therapy for triple-negative breast tumors: SMAD7 increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 18/December/2016, 10.40 pm

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]
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December 18, 2016
Published by admin_auro at December 18, 2016
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Molecular therapy for Bone disorders: MiR-143 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 18/December/2016, 10.33 pm

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone […]
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