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December 13, 2016
Published by admin_auro at December 13, 2016
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Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Kuwanon V, one of the constituents of Mulberry, increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 13/December/2016, 11.35 pm

From Significance of the study to Public health relevance: Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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December 13, 2016
Published by admin_auro at December 13, 2016
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Natural product-derived Life-extension therapy: Cinnamaldehyde, one of the constituents of Cinnamon, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 13/December/2016, 11.16 pm

What they say? A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows […]
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December 13, 2016
Published by admin_auro at December 13, 2016
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Natural product-derived therapy for Human Leukemias: Grifolin, an antitumor natural product from mushroom Albatrellus confluens, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 13/December/2016, 11.01 pm

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms […]
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December 13, 2016
Published by admin_auro at December 13, 2016
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Molecular therapy for Myocardial Infarction: Snail/SNAI1 (snail family zinc finger 1), a positive regulator of epithelial-mesenchymal transition, inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 13/December/2016, 10.42 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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