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December 16, 2016
Published by admin_auro at December 16, 2016
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Small molecule-based PD-1 pathway blockade for Human cancer therapy: Lithium increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 16/December/2016, 1.21 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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December 15, 2016
Published by admin_auro at December 15, 2016
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Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses. Naringenin, a flavone found in grapefruit, decreases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 15/December/2015, 11.04 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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December 15, 2016
Published by admin_auro at December 15, 2016
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Life-extension therapy: MiRNA-1827 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 15/December/2016, 10.57 pm

What they say? A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows […]
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December 15, 2016
Published by admin_auro at December 15, 2016
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Natural product-derived therapy for Human Leukemias: Kukoamine A (KuA), a spermine alkaloid derived from Cortex lycii radicis and Lycium chinense among others, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 15/December/2016, 10.53 pm

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms […]
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