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October 3, 2016

Natural product therapy for KRAS-mutant lung cancer: Thymoquinone, the most abundant component in Black Cumin – Nigella sativa, decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 03/October/2016, 10.59 am

A recent study from the Department of Cell Biology, University of Texas Southwestern Medical Center, Texas 75390, USA shows that XPO1 can be pharmacologically targeted in KRAS-mutant lung […]
October 2, 2016

Natural product Life-extension therapy: Bergapten (5-methoxypsoralen), a natural psoralen derivative present in many fruits and vegetables, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 2/October/2016, 8.00 am

On the eve of Mahatma Gandhi Birth Anniversary ********* We wish everyone a happy Mahatma Gandhi Jayanti 2016. On this special occasion, we are happy to announce that Ideas posted today (02/October/2016) will […]
October 2, 2016

Anti-telomerase cancer therapy: MIR-138-3p suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down regulation of its target gene, 2/October/2016, 7.20 am

On the eve of Mahatma Gandhi Birth Anniversary ********* We wish everyone a happy Mahatma Gandhi Jayanti 2016. On this special occasion, we are happy to announce that Ideas posted today (02/October/2016) will […]
October 1, 2016

Natural product therapy for pulmonary arterial hypertension: Thymoquinone, the most abundant component in Black Cumin – Nigella sativa, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/October/2016, 11.29 pm

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
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