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November 24, 2016
Published by admin_auro at November 24, 2016
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Natural product-derived combo therapy for ACAT1-overexpressing Human cancers: Curcumin and (6)-gingerol (6G) combo, one of the main components of Turmeric and Ginger, respectively, inhibits Mitochondrial acetyl-CoA acetyltransferase 1 (ACAT1) expression, acetylation of Pyruvate dehydrogenase (PDH) and PDH phosphatase, pyruvate dehydrogenase complex (PDC) formation and tumor growth via down regulation of its target gene, 24/November/2015, 2.57 pm

Introduction: What they say A study from the Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, […]
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November 24, 2016
Published by admin_auro at November 24, 2016
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Molecular therapy for Metabolic disorders: MiRNA-152 increases (LXR)-α expression, insulin-secreting cell mass and function via down regulation of its target genes, 24/November/2016, 1.27 pm

Public health relevance:  Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to treat […]
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November 24, 2016
Published by admin_auro at November 24, 2016
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Anti-telomerase cancer therapy: MiRNA-1827 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 24/November/2016, 8.49 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]
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November 24, 2016
Published by admin_auro at November 24, 2016
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Anti-metastasis therapy: MiRNA-9600 increases the expression of metastasis suppressor BTG2 and inhibits proliferation, invasion and metastasis of cancer cells via down regulation of its target gene,23/November/2015, 6.06 am

Research findings to Therapeutic opportunity:  The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of metastasis suppressor […]
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