admin_auro

December 3, 2016
Published by admin_auro at December 3, 2016
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Natural product Life-extension therapy: EHHM (E‑[6′-(5′-hydroxypentyl)tricosyl]-4-hydroxy-3-methoxycinnamate), found in Livistona Chinensis, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 3/December/2016, 5.57 pm

What they say? A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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December 3, 2016
Published by admin_auro at December 3, 2016
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Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses: Kukoamine A (KuA), a spermine alkaloid derived from Cortex lycii radicis and Lycium chinense among others, decreases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 3/December/2015, 5.38 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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December 3, 2016
Published by admin_auro at December 3, 2016
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Natural product-derived therapy for Myocardial Infarction: Guggulsterone (4,17(20)-pregnadiene-3,16-dione), a resin found in the Guggul herb Commiphora mukul, inhibits DNA damage responses, and telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 3/December/2016, 6.55 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 2, 2016
Published by admin_auro at December 2, 2016
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Natural product Life-span extension therapy: Ferulic acid, found abundantly in the flax seeds, refined maize bran and soft and hard rice bran among others, may increase life span by suppressing mTOR pathway, 2/December/2016, 11.27 pm

What is known:  It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity […]
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