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November 28, 2016
Published by admin_auro at November 28, 2016
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Natural product Life-span extension therapy: N(1), N(11)-Diethylnorspermine, a spermine analog, may increase life span by suppressing mTOR pathway, 28/November/2016, 11.13 pm

What is known:  It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity […]
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November 28, 2016
Published by admin_auro at November 28, 2016
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Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Eriocitrin, isolated from lemons, increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 28/November/2015, 10.45 pm

Introduction: What they say:  A study from the Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA shows […]
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November 28, 2016
Published by admin_auro at November 28, 2016
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Molecular therapy for triple-negative breast tumors: BMP4 increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 28/November/2015, 7.04 pm

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]
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November 28, 2016
Published by admin_auro at November 28, 2016
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Anti-metastasis therapy: Anticancer drug Campothecin (CPT) decreases PDPN expression, invasion, migration and metastasis of tumor cells via up regulation of its target gene, 28/November/2016, 6.55 pm

Research findings to Therapeutic opportunity:  The study presented here suggests that Anticancer drug Campothecin (CPT), by increasing the expression of its target genes, it may decrease the […]
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