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November 18, 2016

Anti-metastasis therapy: MiRNA-9600 increases the expression of TPM1 (tropomyosin) and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 18/November/2015, 11.41 pm

Research findings to Therapeutic opportunity:  The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of TPM1 (tropomyosin). […]
November 18, 2016

Anti-telomerase cancer therapy: MiRNA-149 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 18/November/2016, 11.14 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]
November 18, 2016

Natural product-based Cardiac rejuvenation therapy: Methyl 3,5-dicaffeoyl quinate (MDQ), a flavonoid glucoside found in Castor-aralia (kalopanax-pictus), Salicornia herbacea L., Aster oharai and Solidago virga-aurea var. gigantean, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 18/November/2015, 7.04 am

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated cardiomyopathy and heart failure […]
November 18, 2016

Natural product therapy for Breast Cancer: Cucurbitacin D, found in Trichosanthes kirilowii (Gualou), Phormium tenaxm, and Luffa amara among others, increases the level of tumor suppressor p53, decreases the expression of metastasis promoter Snail1, inhibits the proliferation of tumor-initiating cells, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 18/November/2015, 6.07 am

Introduction: What they say:  A study from the Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann […]
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