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April 9, 2019

Published by admin_auro at April 9, 2019

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Intracardiac injection of Lansoprazole promotes heart regeneration and repair: Intracardiac injection of Lansoprazole (trade name: Prevacid) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 9/April/2019, 11.00 pm

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]

April 8, 2019

Published by admin_auro at April 8, 2019

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Probiotic-based therapy for tuberculosis: Probiotic Lactobacillus fermentum CQPC08 (LFCQPC08) deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via upregulation of its target gene, 8/April/2019, 11.53 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]

April 8, 2019

Published by admin_auro at April 8, 2019

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Mechanistic insights into why consumption of high fact diet is bad for your heart: High fat diet promotes DNA damage responses, decreases telomerase expression, accelerates telomere shortening, and decreases cardiomyocyte survival after myocardial infarction, via downregulation of PNUTS, 8/April/2019, 11.38 pm

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac aging and function.” This study was published, in the 7 March 2013 issue of the […]

April 8, 2019

Published by admin_auro at April 8, 2019

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Molecular therapy for cardiac dysfunction: Lansoprazole (trade name: Prevacid), a medication used to decrease stomach acid secretion, decreases Mir-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function, via upregulation of its target gene, 8/April/2018, 11.14 pm

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]