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November 24, 2016

Published by admin_auro at November 24, 2016

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Anti-telomerase cancer therapy: MiRNA-1827 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 24/November/2016, 8.49 am

Introduction: What they say: The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]

November 24, 2016

Published by admin_auro at November 24, 2016

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Ideas

Anti-metastasis therapy: MiRNA-9600 increases the expression of metastasis suppressor BTG2 and inhibits proliferation, invasion and metastasis of cancer cells via down regulation of its target gene,23/November/2015, 6.06 am

Research findings to Therapeutic opportunity: The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of metastasis suppressor […]

November 23, 2016

Published by admin_auro at November 23, 2016

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Natural product therapy for glucose homeostasis and TIIDM: Areca nut extract or Arecoline increases IKKß and XBP1s activity, decreases the levels of tumor suppressor/stress-responsive proteins, such as PDCD4, and PTEN, reduces ER stress, improves insulin sensitivity, promotes glucose homeostasis and prevents the progression of TIIDM via up regulation of its target gene, 23/November/2015, 2.54 pm

What they say: A study from the Division of Endocrinology, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02130, USA; Laboratory of Gene Regulation and Signal […]

November 23, 2016

Published by admin_auro at November 23, 2016

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Natural product-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients:Persimmon tannin increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 23/November/2016, 2.51 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte […]