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November 13, 2016
Published by admin_auro at November 13, 2016
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Natural product Life-span extension therapy: (+)-Syringaresinol, isolated from Panax ginseng berry, & Prunus mume, among others, increases life span by suppressing mTOR pathway through up regulation of its target gene, 13/November/2016, 11.26 am

What is known: It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity […]
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November 13, 2016
Published by admin_auro at November 13, 2016
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Natural product therapy for KRAS-mutant lung cancer: Epigallocatechin gallate, one of the main components of Green tea, decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 13/November/2016, 9.20 am

What they say:  A recent study from the Department of Cell Biology, University of Texas Southwestern Medical Center, Texas 75390, USA shows that XPO1 can be pharmacologically targeted […]
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November 13, 2016
Published by admin_auro at November 13, 2016
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MiRNA-based therapy for Breast Cancer: MiRNA-137 increases the level of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 13/November/2015, 9.01 am

What they say:  A study from the Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann Arbor, […]
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November 12, 2016
Published by admin_auro at November 12, 2016
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Molecular therapy for Myocardial Infarction: miR-380-5p improves myocardial function after myocardial infarction via up-regulation of PNUTS, 11/November/2016, 11.22 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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