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November 27, 2016
Published by admin_auro at November 27, 2016
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Antimetastasis therapy: MiRNA-9600 increases the expression of tumor suppressor long ncRNA GAS5 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 27/November/2016, 8.29 pm

Research findings to Therapeutic opportunity:  The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of tumor suppressor […]
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November 27, 2016
Published by admin_auro at November 27, 2016
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Anti-metastasis therapy: Tumor suppressor ING1b/p33 decreases PDPN expression, invasion, migration and metastasis of tumor cells via up regulation of its target gene, 27/November/2015, 8.16 pm

Research findings to Therapeutic opportunity:  The study presented here suggests that tumor suppressor ING1b/p33, by increasing the expression of its target genes, it may decrease the expression […]
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November 27, 2016
Published by admin_auro at November 27, 2016
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Molecular therapy for Bone disorders: MiR-188 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 27/November/2016, 8.10 pm

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone […]
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November 27, 2016
Published by admin_auro at November 27, 2016
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Molecular therapy for KRAS-mutant lung cancer: UBTD1 (Ubiquitin domain containing 1) decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 27/November/2016, 8.03 pm

What they say:  A recent study from the Department of Cell Biology, University of Texas Southwestern Medical Center, Texas 75390, USA shows that XPO1 can be pharmacologically targeted […]
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