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April 26, 2015

MiRNA-based Exercise-Mimicking pill may inhibit Insulin resistance: MiRNA-196a decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, and improves insulin sensivitity via down regulation of its target gene, 26/April/2015, 9.23 am

Significance: This study suggests, for the first time, that MiRNA-196a , by decreasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, […]
April 26, 2015

Exposure to sunlight stalls Cancer stem cell proliferation and metastatic cancer progression: Calcitriol (1α, 25-dihydroxyvitamin D3) decreases the expression of cancer stem-cell enriched reprogramming protein Oct4 and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 26/April/2015, 9.07 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-cancer stem cell/metastasis therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its […]
April 26, 2015

Anti-aging and Lifespan extension therapy: Orphan nuclear receptor NUR77 increases the expression of immortality gene telomerase via up regulation of its target gene, 26/April/2015, 8.11 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Anti-aging and Lifespan extension therapy:  Orphan nuclear receptor NUR77 increases the expression of immortality gene telomerase  via […]
April 26, 2015

Natural product-based therapy for pulmonary arterial hypertension: Nordihydroguaiaretic acid (NDGA) inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 26/April/2015, 08.06 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
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