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April 26, 2015
Published by admin_auro at April 26, 2015
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A known drug of an unknown analgesic  function: Metformin, the widely used drug in the treatment of TIIDM,  suppresses the expression of Cyclooxygenase-2 (Cox2) via up regulation of its target gene, 26/April/2014, 23.38

Significance:  Meformin is widely used drug in the treatment of TIIDM, while Cyclooxygenase-2  (COX2) inhibitors  are used to relieve pain. This study suggests, for the first time, that […]
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April 26, 2015
Published by admin_auro at April 26, 2015
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Molecular therapy for Metastatic human tumors: Ndfip1 decreases cellular proliferation, invasion and metastasis by increasing the expression of metastasis suppressor TPM1 (Tropomyosin-1) via down regulation of its target gene, 26/April/2015, 18.09

A study from the Cell Pathology Division, The Children’s Hospital of Philadelphia, Philadelphia, USA shows that “TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production […]
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April 26, 2015
Published by admin_auro at April 26, 2015
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Molecular cancer therapy: JunB inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 26/April/2015, 17.16

A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.  This study was published in the April 10, 2014 Nature [I.F >42] by Prof. Thomas H, […]
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April 26, 2015
Published by admin_auro at April 26, 2015
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Natural product-based Regenerative therapy for T2D: Phlorotannin, isolated from the edible brown alga Ecklonia stolonifera, promotes reprogramming of adult pancreatic ductal cells into α, δ, and β cells via up regulation of Ngn3, 26/April/2015, 10.00 am

A recent study from the Mammalian Genetics Laboratory, Cancer Research UK London Research Institute, Lincoln’s Inn Fields Laboratories, London, United Kingdom; and School of Medicine, King’s College […]
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