Insights into How alcohol consumption promotes cognitive deficits: Prolonged excess consumption of Ethanol promotes cognitive deficits via up regulation of its target gene, 25/October/2014, 22.16

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Insights into How alcohol consumption promotes cognitive deficits: Prolonged excess consumption of Ethanol promotes cognitive deficits via up regulation of its target gene, 25/October/2014, 22.16,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Amount: $ 300 Undisclosed information: A mechanistic insight into […]

Chemopreventive therapy against Metastatic cancer: Germinated brown rice (GBR) extract increases the expression of tumor suppressor INK4a/ARF via down regulation of its target gene, 25/October/2014, 21.01

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Chemopreventive therapy against Metastatic cancer: Germinated brown rice (GBR) extract increases the expression of tumor suppressor INK4a/ARF  via down regulation of its target gene, 25/October/2014, 21.01,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Amount: $ 300 Undisclosed information: A mechanistic insight into how Germinated brown rice (GBR) […]

Interleukin-based therapy for Metabolic disorders: c-Myc increases insulin sensitivity, restores mucosal immunity and decreases endotoxaemia via up regulation of Interleukin-22, 25/October/2014, 11.26

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Interleukin-based therapy for Metabolic disorders: c-Myc increases insulin sensitivity, restores mucosal immunity and decreases endotoxaemia via up regulation of  Interleukin-22, 25/October/2014, 11.26, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: This study suggests, for the first time, that c-Myc, by […]

Mechanism of tumorigenesis: RREB increases the expression of Notch-1 and -2 via down regulation of its target gene, 25/October/2014, 11.13 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, Mechanism of tumorigenesis: RREB increases the expression of Notch-1 and -2 via down regulation of its target gene, 25/October/2014, 11.13 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that RREB, by decreasing the expression of its target gene, it may increase the expression of Notch1 and Notch2. Thus, pharmacological formulations encompassing “RREB inhibitor“ may be used to inhibit tumorigenesis […]

Natural product-based therapy for Hypertension: Silvestrol rescues pulmonary arterial hypertension via down regulation of its target gene, 25/October/2014, 11.07 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, Natural product-based therapy for Hypertension: Silvestrol rescues pulmonary arterial hypertension via down regulation of its target gene, 25/October/2014, 11.08 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that Silvestrol, by decreasing the expression of its target gene,  it may rescue pulmonary arterial hypertension. Thus, pharmacological formulations encompassing “Silvestrol or its analogues“ may be used to treat pulmonary […]

Natural product-based therapy for DM: Mangiferin, a compound isolated from Mango, inhibits gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, 25/September/2014, 11.03 am

A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA; and others shows that “Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression.” This study was published in the June 26, 2014 Nature [I.F >35] by Prof. Puigserver and others from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA. […]