Therapeutic insight into the treatment of Age-related Cataract: Stem cell protein Oct-4 promotes the surivival of lens epithelial cells via up regulation of its target gene, 21/October/2014, 11.43 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, L., Therapeutic insight into the treatment of Age-related Cataract: Stem cell protein Oct-4 promotes the surivival of lens epithelial cells via up regulation of its target gene, 21/October/2014, 11.43 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests that Oct-4, by increasing the expression of its target gene, it may decrease the expression of a […]
Anti-metastasis therapy: SMAD7 inhibits invasive motility via down regulation of ICAT (Inhibitor of β-catenin and TCF), 21/October/2014, 9.41 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, L., Anti-metastasis therapy: SMAD7 inhibits invasive motility via down regulation of ICAT (Inhibitor of β-catenin and TCF), 21/October/2014, 9.41 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests that SMAD7, by increasing the expression of its target gene, it may decrease the expression of EMT protein ICAT. Therefore, pharmacological formulations encompassing “SMAD7 activators“ may be used to treat metastatic cancers. […]
Therapeutic insights into increasing the life expectancy of Males: Mangiferin, a compound isolated from Mango, increases male longevity via up regulation of its target gene, 21/October/2014, 9.37 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Therapeutic insights into increasing the life expectancy of Males: Mangiferin, a compound isolated from Mango, increases male longevity via up regulation of its target gene, 21/October/2014, 9.38 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: Numerous studies show that Mango has health benefits. This study suggests, for the first time, that Mangiferin, […]
MiRNA-based Regenerative therapy for DM: HIF1α increases insulin-secreting cell mass and function via up regulation of its target genes, 21/October/2014, 9.21 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based Regenerative therapy for DM: HIF1α increases insulin-secreting cell mass and function via up regulation of its target genes, 21/October/2014, 9.21 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests, for the first time, that HIF1α, by increasing the expression of its target gene, it may increase insulin-secreting cell mass and function. Thereby, it may increase the insulin sensitivity of […]
Anti-metastasis therapy: Angiopoietin-like protein 1 increases the expression of tumor suppressor miRNA Let-7 via down regulation of its target gene, 21/October/2014, 8.47 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, L., Anti-metastasis therapy: Angiopoietin-like protein 1 increases the expression of tumor suppressor miRNA Let-7 via down regulation of its target gene, 21/October/2014, 8.47 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests that Angiopoietin-like protein 1, by decreasing the expression of its target gene, it may increase the expression of let-7. Thus, pharmacological formulations encompassing “Angiopoietin-like […]
Mechanistic & therapeutic insights into tumorigenesis: SNAI2 suppresses the expression of a number of tumor suppressor miRNAs via down regulation of its target gene, 21/October/2014, 8.40 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Citation: Boominathan, Mechanistic & therapeutic insights into tumorigenesis: SNAI2 suppresses the expression of a number of tumor suppressor miRNAs via down regulation of its target gene, 21/October/2014, 8.40 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: This study suggests that EMT protein SNAI2, by decreasing the expression of its target gene, it may increase the expression of number of tumor […]