Natural product-based therapy for Alzheimer’s disease: Rhamnetin, an O-methylated flavonol isolated from cloves, decreases Tau expression via up regulation of its target gene, 14/October/2014, 6.34 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based therapy for Alzheimer’s disease: Rhamnetin, an O-methylated flavonol isolated from cloves, decreases Tau expression via up regulation of its target gene, 14/October/2014, 6.34 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: It has been shown that decreasing the expression of Tau protein alleviates the pathogenic symptoms-associated with Alzheimer’s disease. This […]
Lifespan extention therapy: Tanshinone IIA, a well known Chinese medicine, increases life expectancy via down regulation of its target gene, 14/October/2014, 6.27 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Lifespan extention therapy: Tanshinone IIA, a well known Chinese medicine, increases life expectancy via down regulation of its target gene, 14/October/2014, 6.27 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation Significance: This study suggests, for the first time, that Tanshinone IIA may extend the lifespan […]
Anti-miRNA based therapy for NIDDM: Increased expression of Stress-responsive miRNA-188 promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1, 13/October/2014, 21.49
A study from the Department of Cancer Biology, Dana-Farber Cancer Institute; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA; and others shows that “Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression.” This study was published in the June 26, 2014 Nature [I.F >42] by Prof. Puigserver and others from the Department of Cancer Biology, Dana-Farber Cancer Institute; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA. […]
Chemopreventive therapy against Human Cancer: Natural product Cucurbitacin I inhibits tumor cell proliferation via down regulation of Superoxide dismutase 1 (SOD1), 13/October/2014, 18.59
The 1989 Nobel prize winner in Physiology/Medicine Prof. Varmus Harold E, Somwar R and others from High Throughput Screening Core Facility, and Organic Synthesis Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; and the US National Cancer Institute, USA has published a research paper in the 27 September 2011 issue of Proc Natl Acad Sci U S A. (I.F: >10) stating that “Superoxide dismutase 1 (SOD1) is a target for a small […]
MiRNA-based Regenerative therapy for T2D: Argonaute-2 (Ago2) promotes reprogramming of adult pancreatic ductal cells into α, δ, and β cells via up regulation of Ngn3, 13/October/2014, 12.21 pm
A recent study from the Mammalian Genetics Laboratory, Cancer Research UK London Research Institute, Lincoln’s Inn Fields Laboratories, London, United Kingdom; and School of Medicine, King’s College London, London, United Kingdom shows that “Loss of Fbw7 Reprograms Adult Pancreatic Ductal Cells into α, δ, and β Cells.” This study was published in the August 7 2014 Cell Stem Cell by Prof Axel Behrens, Rocio Sancho, and […]
Natural product-based therapy for Hypertension: Fangchinoline, an anti-inflammatory and anti-cancerous compound isolated from Stephania, decreases renal oxidative stress and blood pressure via up regulation of its target gene, 13/October/2014, 11.58 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based therapy for Hypertension: Fangchinoline, an anti-inflammatory and anti-cancerous compound isolated from Stephania, decreases renal oxidative stress and blood pressure via up regulation of its target gene, 13/October/2014, 11.58 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance: It has been shown that accumulation of excessive renal reactive oxygen species (ROS) […]