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April 13, 2015

Stalling metastatic cancer spread by exposing it to the Sunlight: Calcitriol (1α, 25-dihydroxyvitamin D3) increases the expression of tumor suppressor Sprouty-1 and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 13/April/2015, 23.14

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-metastasis therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its target genes, […]
April 13, 2015

Natural product-based Life-span extension therapy: A. officinarum ethanol extract (AOE) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 13/April/2015, 22.59

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 […]
April 13, 2015

MiRNA-based therapy for acute respiratory distress syndrome: MiRNA-302b inhibits acute lung injury via down regulation of its target gene, 13/April/2015, 22.54

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based therapy for acute respiratory distress syndrome: MiRNA-302b inhibits acute lung injury via down regulation of its […]
April 13, 2015

Natural product-based therapy for pulmonary arterial hypertension: S-Allyl cysteine (SAC), a component of Garlic, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 13/April/2015, 22.51

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
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