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April 27, 2015

Small RNA-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients: MiRNA-27 increases the expression of ERBB2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 27/April/2014, 11.48 am

A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
April 27, 2015

Small RNAs not only cure T2DM, but also extend lifespan: MiRNA-216b increases UCP protein expression, energy expenditure, glucose tolerance, insulin sensitivity and extends lifespan via down regulation of its target gene, 27/April/2015, 10.48 am

A study from the Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Diabetes Unit, Medical Services, Massachusetts General Hospital, Boston, MA 02114, USA; […]
April 27, 2015

Sunlight exposure stalls Cancer stem cell proliferation and metastatic cancer progression: Calcitriol (1α, 25-dihydroxyvitamin D3) decreases the expression of cancer stem-cell enriched reprogramming protein Nanog and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 27/April/2015, 8.33 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-cancer stem cell/metastasis therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its […]
April 27, 2015

The Exercise-Mimicking pills may inhibit Insulin resistance and decrease adiposity: HMGB1 decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, improves muscle insulin sensivitity and decreases adiposity via up regulation of its target gene, 27/April/2015, 8.01 am

Significance: This study suggests, for the first time, that HMGB1, by increasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
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