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April 2, 2015

Molecular therapy for DM: Ars2 (arsenite-resistance protein 2/Serrate RNA effector molecule homolog) inhibits gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, 2/April/2015, 12.01 pm

A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA; and others shows that “Cyclin D1–Cdk4 controls glucose metabolism independently of […]
April 2, 2015

Small molecule-based Life-span extension therapy: Sox2 inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 2/April/2015, 11.26 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Small molecule-based Life-span extension therapy: Sox2 inhibits senescence and  extends life span by down regulating the […]
April 2, 2015

Molecular therapy for pulmonary arterial hypertension: Succinate, an intermediate in the TCA cycle, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene, 2/April/2015, 10.57 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
April 2, 2015

Natural product-based therapy for hypertensive cardiovascular diseases: EF24 (curcumin analog) suppresses Ang II-induced hypertensive cardiac remodelling via down regulation of its target gene, 2/April/2015, 07.04 am

A recent study from the Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China shows that “Smad7 inhibits angiotensin II-induced hypertensive […]
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