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March 28, 2015
Published by admin_auro at March 28, 2015
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Small molecule-based therapy for Myocardial Infarction: Resveratrol, an activator of longevity promoting gene Sirtuin-1, improves ageing- and stress-associated decline in cardiac function via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 28/March/2015, 09.46 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On […]
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March 28, 2015
Published by admin_auro at March 28, 2015
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Mechanistic insight into tumor suppression: TAp63 promotes phosphorylation of tumor suppressor p53 (on Ser15) and via up regulation of its target gene, 28/March/2015, 9.39 am

Significance: This study suggests, for the first time, that TAp63, by increasing the expression of its target gene, it may phosphorylate tumor suppressor p53 (on Ser15). Thereby, […]
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March 28, 2015
Published by admin_auro at March 28, 2015
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Small molecule-based Life-span extension therapy: LKB1 inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 28/March/2014, 9.30 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Small molecule-based Life-span extension therapy: LKB1 inhibits senescence and  extends life span by down regulating the […]
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March 28, 2015
Published by admin_auro at March 28, 2015
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Small molecule-based Life-span extension therapy: Succinate, an intermediate in the TCA cycle, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 28/March/2015, 9.28 am

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 […]
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