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April 26, 2015

Natural product-based therapy for pulmonary arterial hypertension: Nordihydroguaiaretic acid (NDGA) inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 26/April/2015, 08.06 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
April 25, 2015

Natural product-based therapy for Metastatic Pancreatic/intestine/ovarian Cancers: Triptolide suppresses the expression of PDGF Receptor β (PDGFRβ) via down regulation of its target gene, 25/April/2014, 22.19

A study from Watson School of Biological Sciences shows that Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling. This study was published in the April 10, […]
April 25, 2015

MiRNA-based therapy for leukaemia: MiRNA-506 suppresess B-cell lineage acute lymphoid leukaemia via down regulation of its target gene, 25/April/2014, 22.11

A recent study from the “Department of Laboratory Medicine, University of California San Francisco, San Francisco, California 94143, USA;  and Department of Haematology, University of Cambridge, […]
April 25, 2015

MiRNA-based Exercise-Mimicking pill may inhibit Insulin resistance: MiRNA-582-5p decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, and improves insulin sensivitity via down regulation of its target gene, 25/April/2015, 22.05

Significance: This study suggests, for the first time, that MiRNA-582-5p, by decreasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
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