Antiviral diseases

September 28, 2017

Natural product-derived antiviral therapy for HIV virus: Nordihydroguaiaretic acid (NDGA), isolated from creosote, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 29/September/2017, 12.40 am

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
September 24, 2017

Natural product-derived therapy for tuberculosis: Withaferin A (WA), isolated form Ashwagantha/Withania sominifera, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/September/2017, 12.05 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
September 24, 2017

Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 24/September/2017, 11.59 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase […]
September 24, 2017

Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Solosodine, isolated from Solanum melongena L, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 24/September/2017, 11.53pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]