Antiviral diseases

September 1, 2017

Natural product-derived antiviral therapy against Hepatitis-B virus: Artemisinin, found abundantly in Artemisia Annua L, increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 2/September/2017,  1.00 am

Introduction: What they say A study from the Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China; and Institute of Immunology, Zhejiang University School […]
August 25, 2017

Natural product-derived antiviral therapy for HIV virus: Ivermectin (Brand name: Heartguard/Mectizen/Stromectol)  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 25/August/2017, 11.46 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
August 22, 2017

Antiviral therapy for Neuroinvasive West Nile virus: Ivermectin (Brand name:Heartguard/Mectizan) increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 22/August/2017, 9.55 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
August 10, 2017

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Auranofin, a drug used in the treatment of Rheumatoid arthritis,  increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 10/August/2017, 10.45 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]