Cancer

June 6, 2017

Natural product-derived therapy for metastasis: Berberine, one of the components of Berberis, Phellodendron amurense, and Guduchi among others, inhibits the expression of IL-6/8, decreases the experssion of down stream molecules WASF3 and Arp2/3, suppresses tumor cell migration, reduces metastasis and prolongs survival via up regulation of its target gene, 6/June/2017, 11.14 pm

Introduction: What they say: A study from Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland 21218, USA; Johns Hopkins Physical Sciences-Oncology Center, […]
June 3, 2017

Anti-telomerase cancer therapy: MiR-30 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 3/June/2017, 11.48 pm

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
May 29, 2017

Natural product-derived therapy for Metastatic cancers: Dihydromyricetin (DHM), found in Ampeopsis Grossdentatam, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 26/May/2017, 12.04 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
May 24, 2017

Natural product-derived therapy for metastatic prostate cancer: Agaricus blazei Murrill (AbM) mushroom extract inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 24/May/2017, 7.29 am

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA […]