Cancer

June 11, 2017

Natural product therapy for KRAS/LKB1-mutant lung cancer: Epigallocatechin gallate (EGCG), isolated from Green tea, increases the levels of tumor suppressor proteins, inhibits the expression of urea cycle enzyme carbamoyl phosphate synthetase-1 (CSP1), decreases pyrimidine pools, stalls DNA synthesis, and inhibits the progression of KRAS/LKB1-mutated lung cancers via up regulation of its target gene, 11/June/2017, 11.46 pm

Introduction: What they say A study from the Children’s Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas 75390, USA; Department of Pediatrics, UT Southwestern […]
June 10, 2017

Narrow-band ultraviolet B therapy for Metastatic cancers: Narrow-band ultraviolet B increases the expression of metastasis suppressors BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 11/June/2017, 12.35 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
June 10, 2017

Anti-telomerase cancer therapy: USF-1 (Upstream Transcription Factor 1) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 11/June/2017, 12.30 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
June 10, 2017

Natural product-derived regenerative therapy for improving memory in aged individuals: L-3-n-butylphthalide (L-NBP), isolated from seeds of Apium graveolens Linn, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 11/June/2017, 12.23 am

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]