Cancer

July 8, 2017

Natural product-derived therapy for prostate cancer: Shikonin, one of the components of Zicao, inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 9/July/2017, 12.09 am

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent […]
July 8, 2017

Anti-telomerase cancer therapy: α-Solanine, isolated from Solanum Nigrum, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 8/July/2017, 11.33 pm

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech, from the BioFrontiers Institute, USA, has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: 43) stating that “The TEL patch of telomere protein TPP1 […]
July 7, 2017

Natural product-derived therapy for Human Leukemias: Dihydromyricetin, isolated from Ampeopsis Grossdentatam, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 7/July/2017, 10.23 pm

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms by […]
July 7, 2017

Anti-telomerase cancer therapy: IRE1α (Inositol requiring enzyme-1) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 7/July/2017, 10.13 pm

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]