Cancer

July 6, 2017

Anti-telomerase cancer therapy: CHOP/GADD153 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 6/July/2017, 7.14 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]
July 6, 2017

Molecular therapy for brain tumor and oesophageal squamous cell carcinoma: Metformin, the widely used drug in the treatment of TIIDM, inhibit the expression of Integrin a7 (ITGA7), impair laminin-induced/FAK mediated signalling, inhibit the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppress tumor cell migration, reduce metastasis and prolong survival via down regulation of its target gene, 6/July/2017, 6.58 am

Introduction: What they say: A study from the Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; Department of Oncology […]
July 4, 2017

Natural product-derived therapy for Metastatic cancers: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemisia Annua L, increases the expression of metastasis/tumor suppressors BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 5/July/2017, 1.00 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half […]
July 3, 2017

Natural product-derived therapy for Metastatic human tumors: A therapeutic mix encompassing Artemisinin and Artesunate, isolated from Artemesia Annua, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 4/July/2017, 1.29 am

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, […]