Cancer

June 29, 2017

Natural product-derived therapy for Metastatic cancers: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemisia Annua L, increases the expression of metastasis promoters TIMP3 and CCM3/KRIT1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 29/June/2017, 11.56 pm pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half […]
June 29, 2017

Natural product-derived therapy for Chronic Myeloid leukaemia (CML): Curcumin, isolated from Turmeric, decreases the expression of Musashi2, inhibits cytosolic aminotransferase BCAT1 expression, decreases the intracellular production of BCAAs (Branched-chain amino acids), increases the expression of tumor suppressor genes, promotes differentiation of CML cells, and inhibits cancer progression in Myeloid leukemia via up-regulation of its target gene, 29/May/2017, 11.56 pm

Introduction: What they say: A study from the Department of Biochemistry-Molecular Biology, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, USA; and […]
June 29, 2017

Natural product therapy for CyclinD3-CDK6 overexpressing cancers: Artemisinin, isolated from Artemisia Annua, increases the levels of tumor suppressor proteins, inhibits the activity of glycolytic enzymes 6-phosphofructokinase and pyruvate kinase M2, decreases antioxidants NADPH and glutathione levels, increases reactive oxygen species levels, promotes apoptosis, and inhibits the progression of CyclinD3-CDK6 overexpressing cancers via down regulation of its target gene, 29/June/2017, 7.29 pm

Introduction: What they say A study from Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; and Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA shows […]
June 27, 2017

Natural product-derived therapy for prostate cancer bone metastasis: Artemisinin, isolated from Artemisia Annua, inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 27/June/2017, 11.24 pm

Introduction: What they say: A study from the Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that “MAOA-Dependent Activation of […]