Cancer

June 27, 2017

Natural product-derived therapy for brain tumor and oesophageal squamous cell carcinoma: Artesunate/Artemisinin, isolated from Artemisia annua, inhibit the expression of Integrin a7 (ITGA7), impair laminin-induced/FAK mediated signalling, inhibit the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppress tumor cell migration, reduce metastasis and prolong survival via down regulation of its target gene, 27/June/2017, 11.08 pm

Introduction: What they say: A study from the Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; […]
June 26, 2017

Natural product-derived therapy for metastasis: Artemisinin, one of the components of Artemisia Annua, inhibits the expression of IL-6/8, decreases the expression of down stream molecules WASF3 and Arp2/3, suppresses tumor cell migration, reduces metastasis and prolongs survival via up regulation of its target gene, 26/June/2017, 11.25 pm

Introduction: What they say: A study from Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland 21218, USA; Johns Hopkins Physical Sciences-Oncology Center, […]
June 26, 2017

Natural product-derived Combination therapy for Squamous cell carcinoma of head and neck (HNSCC): A therapeutic mix encompassing an anticancer drug, 1,25-dihydroxyvitamin D and Artemisinin may decrease BMI1 and AP-1 expression, overcome chemotherapeutic resistance, promote chemosensitivity, suppress cancer stem cells in HNSCC, and inhibit lymph node metastasis via down regulation of its target genes, 26/June/2017, 10.56 pm

Introduction: What they say: A study from the Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, Jonsson Comprehensive Cancer Center and Broad Stem Cell Research […]
June 24, 2017

Vitamin-based therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Cholecalciferol, a form of Vitamin-D3, decreases the expression of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 24/June/2017, 11.59 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]