July 23, 2017

Hydrogen Sulfide (H2S)-based therapy for TIIDM and obesity-associated metabolic deficits: Hydrogen Sulfide (H2S) increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 23/July/2017, 11.52 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]
July 23, 2017

Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:  Artesunate, a derivative of artemisinin isolated from Artemesia annal l, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 23/July/2017, 11.41 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
July 23, 2017

Natural product-based therapy for glucose homeostasis and TIIDM: Artesunate, a derivative of artemisinin isolated from Artemesia Annua L, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of  Sox4 and its target gene Amysin,  23/July/2017, 11.33 pm

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in the September 14, 2014 issue of […]
July 22, 2017

Natural product-derived therapy for therapy-resistant cancers: γ-bisabolene, one of the components of Cardamom, inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 22/July/2017, 11.59 pm

Introduction: What they say: A study from Broad Institute, Cambridge, Massachusetts, USA, Howard Hughes Medical Institute, Chevy Chase, Maryland and Department of Chemistry and Chemical Biology, Harvard University, Oxford St., […]