Heart attack

December 5, 2017

Cardiac rejuvenation therapy: Rotigotine, an antidepressant drug, suppresses tumor suppressor INK4a/p16 expression, promotes cardiac repair, delays cardiac ageing and senescence, and extends life span via up regulation of its target gene, 5/December/2017, 11.43 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Cardiac rejuvenation therapy: Rotigotine, an antidepressant drug, suppresses tumor suppressor INK4a/p16 expression, promotes cardiac repair, […]
December 4, 2017

Antidepressants as Cardioprotective agents: Paroxetine (Trade name: Paxil and Seroxat), an antidepressant, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 4/December/2017, 11.48 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
December 4, 2017

Combinatorial therapy for Cardiomyopathy: A therapeutic mix encompassing Paroxetine and Astaxanthin (PA) decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 4/December/2017,  11.40 pm

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
December 4, 2017

Natural product-derived therapy for attenuating pathogenesis of Myocardial infarction: (–)-Catechin, found abundantly in Camellia Sinensis, decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 4/December/2017, 11.14 pm

Introduction: What they say: A recent study from Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Center for Systems […]