Ideas

April 30, 2017

Natural product-derived therapy for Metastatic cancers: Solasodine, found in Solanum melongena, decreases the expression of metastasis promoters TIMP3 and CCM3/KRIT1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 30/April/2017, 6.08 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
April 30, 2017

Natural product therapy for TIIDM and Metabolic defects: Piceatannol, isolated from Norway Spruce, and Aiphanes horrida among others, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 30/April/2017, 5.30 pm

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]
April 29, 2017

Molecular therapy for prostate cancer bone metastasis: Dinaciclib, a Cyclin-dependent kinase inhibitor, inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 29/April/2017, 11.35 pm

Introduction: What they say: A study from the Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that “MAOA-Dependent Activation of […]
April 29, 2017

Natural product therapy for TIIDM and Metabolic defects: Fisetin, found in Strawberries, A. Berlandieri, and A. Greggii among others, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/April/2017, 5.28 pm

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]