Ideas

June 26, 2017

Natural product-based therapy for Inflammatory bowel disease: Methyl Jasmonate (MeJA), isolated from Jasmine, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 27/June/2017, 12.23 am

Introduction: What they say: A study from the Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK Translational Gastroenterology Unit, Nuffield Department of Medicine, University of […]
June 26, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Astaxanthin, isolated from green algae heaematococcus pluvialis, Pandalus, and Phaffia, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of its target gene Sox4, 26/June/2017, 11.58 pm

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in […]
June 26, 2017

Natural product-derived therapy for metastasis: Artemisinin, one of the components of Artemisia Annua, inhibits the expression of IL-6/8, decreases the expression of down stream molecules WASF3 and Arp2/3, suppresses tumor cell migration, reduces metastasis and prolongs survival via up regulation of its target gene, 26/June/2017, 11.25 pm

Introduction: What they say: A study from Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland 21218, USA; Johns Hopkins Physical Sciences-Oncology Center, […]
June 26, 2017

Natural product-derived Combination therapy for Squamous cell carcinoma of head and neck (HNSCC): A therapeutic mix encompassing an anticancer drug, 1,25-dihydroxyvitamin D and Artemisinin may decrease BMI1 and AP-1 expression, overcome chemotherapeutic resistance, promote chemosensitivity, suppress cancer stem cells in HNSCC, and inhibit lymph node metastasis via down regulation of its target genes, 26/June/2017, 10.56 pm

Introduction: What they say: A study from the Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, Jonsson Comprehensive Cancer Center and Broad Stem Cell Research […]