Ideas

January 11, 2019

Published by admin_auro at January 11, 2019

Categories

Molecular therapy for heart regeneration and repair: Metoprolol (trade name: Lopressor), used to treat high blood pressure and heart pain, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 11/January/2017, 10.24 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]

January 8, 2019

Published by admin_auro at January 8, 2019

Categories

Ribonucleic acid-based therapy for Myocardial Infarction: LncRNA ATB inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 9/January/2019, 12.28 am

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March 2013 issue of of […]

January 8, 2019

Published by admin_auro at January 8, 2019

Categories

Ribonucleic acid-based therapy for glucose homeostasis and TIIDM: LncRNA H19 increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM, via down regulation of its target gene, 9/January/2019, 12.19 am

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]

January 8, 2019

Published by admin_auro at January 8, 2019

Categories

Repurposing the anti-hypertensive agent Felodipine into an anti-diabetic agent: Felodipine (Trade name: Plendil), an antihypertensive agent, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of its target gene Lin28, 9/January/2019, 12.12 am

Introduction: What they say: A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]