Ideas

October 22, 2018
Published by admin_auro at October 22, 2018
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Taming cancers with anti-tapeworm drugs: Niclosamide (brand name: Niclocide, Fenasal, Phenasal), an anti-tapeworm drug,  increases the expression of tumor suppressors genes, such as TIMP3, PDCD4, p53, TAp63, TAp73, INK4a/ARF, and others, and induces regression of p53-mutated human cancers and other cancers, via up-regulation of its target gene, 22/October/2018, 10.13  pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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October 22, 2018
Published by admin_auro at October 22, 2018
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Mechanistic insights into how Diazoxide functions as a learning/memory/cognitive-enhancer: Diazoxide (brand name: Proglycem), a vasodilator used in the treatment of hypertension, insulinoma etc.,, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down regulation of its target genes, 22/October/2018, 10.02 pm

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
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October 21, 2018
Published by admin_auro at October 21, 2018
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Stalling arthritic pain with probiotics: Probiotic Bacillus clousii increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 21/October/2018, 1o.33 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
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October 21, 2018
Published by admin_auro at October 21, 2018
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The tiny probiotic Lactobacillus sakei K17 may function as a Pain medication:  Probiotic Lactobacillus sakei K17 increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 21/October/2018, 10.17 pm

 Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
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