Ideas

June 7, 2018

Feel-good hormone may help you live longer: Oxytocin-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Oxytocin, Catalpol, Isoliquiritigenin, Maresin, DIM, Ursolic acid  Lutein, Maresin, Cholecalciferol (OCIMDULMC) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 7/June/2017, 5.58 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
June 6, 2018

Cluster of differentiation-based therapy for body weight control, energy homeostasis and TIIDM: Cluster of differentiation (CD24) decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 6/June/2017, 11.52 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
June 3, 2018

Combinatorial therapy for Deafness: A therapeutic mix encompassing Brmocriptine, Cholecalciferol, Ajoene and DIM (BCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 3/June/2018, 11.25 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Combinatorial therapy for Deafness: A therapeutic mix encompassing Brmocriptine, Cholecalciferol, Ajoene and DIM (BCAD)  increases the […]
June 3, 2018

A ceramide way to treat Non-alcoholic fatty liver disease (NAFLD): α-galactosylceramide promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 3/June/2018, 11.18 pm

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
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