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Ideas

March 17, 2018

Sugar-based therapy for Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 17/March/2018, 7.23 am

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 17, 2018

A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: D-Allose, an aldohexose sugar and C-3 epimer of glucose, may increase life span via up-regulation of its target gene BubR1, 17/March/2018, 7.07 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
March 17, 2018

Natural product-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Spermidine, a natural polyamine, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 17/March/2018, 6.50 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
March 16, 2018

A sweet way to say no to pain: Sugar-based PD-1 pathway activation for Pain therapy: Phyllodulcin, a natural sweetener 400-800 times sweeter than sugar, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 16/March/2017, 7.40 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
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