Ideas

A sweet way to extend lifespan-too good to be true: Polysaccharide-based therapy for lifespan and healthspan extension: Astragalus polysaccharide, isolated from astragalus membraneous, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, 26/July/2018, 12.38 am
A sweet way to extend lifespan-too good to be true: Polysaccharide-based therapy for lifespan and healthspan extension: Astragalus polysaccharide, isolated from astragalus membraneous, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, 26/July/2018, 12.38 am 960 720 Dr Boomi's Genom-2-Discovery Center

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Unknown function of a known vaccine in the treatment of muscle atrophy and wasting: TB/BCG vaccine,  a tuberculosis vaccine,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting, via upregulation of its target gene, 25/July/2018, 11.49 pm
Unknown function of a known vaccine in the treatment of muscle atrophy and wasting: TB/BCG vaccine,  a tuberculosis vaccine,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting, via upregulation of its target gene, 25/July/2018, 11.49 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard Lyon, INSA Lyon, Oullins,…

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Vaccinate yourself with TB vaccine to lead a pain-free life: TB/BCG vaccine-based activation of the PD-1 pathway for Pain therapy: TB/BCG vaccine, a tuberculosis vaccine,  increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 25/July/2018, 11.20 pm
Vaccinate yourself with TB vaccine to lead a pain-free life: TB/BCG vaccine-based activation of the PD-1 pathway for Pain therapy: TB/BCG vaccine, a tuberculosis vaccine,  increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 25/July/2018, 11.20 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 Introduction: What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University,…

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Vasoactive intestinal polypeptide (VIP)-based therapy for blood sugar disease (autoimmune diabetes (TIDM)): Vasoactive intestinal polypeptide (VIP), a peptide hormone known to play a role in heart contractility, vasodilation, and blood pressure,  increases PD-L1 expression,  augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 24/July/2018,  10.24 pm
Vasoactive intestinal polypeptide (VIP)-based therapy for blood sugar disease (autoimmune diabetes (TIDM)): Vasoactive intestinal polypeptide (VIP), a peptide hormone known to play a role in heart contractility, vasodilation, and blood pressure,  increases PD-L1 expression,  augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 24/July/2018,  10.24 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of…

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A sweet way to lengthen lifespan: Astragalus polysaccharide, isolated from astragalus membraneous,  may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 23/July/2018, 11.58 pm
A sweet way to lengthen lifespan: Astragalus polysaccharide, isolated from astragalus membraneous,  may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 23/July/2018, 11.58 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Unearthing an unknown function of a  known vaccine in regenerative muscle atrophy: Repurposing the tuberculosis(TB) vaccine into a muscular dystrophy vaccine: BCG/TB vaccine increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via upregulation of its target gene, 23/July/2018, 11.49 pm
Unearthing an unknown function of a  known vaccine in regenerative muscle atrophy: Repurposing the tuberculosis(TB) vaccine into a muscular dystrophy vaccine: BCG/TB vaccine increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via upregulation of its target gene, 23/July/2018, 11.49 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of…

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