Ideas

August 11, 2018
Published by admin_auro at August 11, 2018
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Androgens are called into action to attenuate arthritic pain: Testosterone-based therapy for inflammation and arthritis:Testosterone, a male reproductive hormone, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 11/August/2018, 8.25 am

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
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August 10, 2018
Published by admin_auro at August 10, 2018
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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others,  increases the expression of tumor suppressors genes, such as  PTPN14, Rb1, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 10/August/2018, 11.03 am

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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August 10, 2018
Published by admin_auro at August 10, 2018
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Assigning an unknown function to a known female reproductive hormone Estrogen in Longevity: Estrogen-based therapy for aging-associated diseases and Lifespan extension: Estrogen, a female steroid hormone, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 10/August/2018, 10.41 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
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August 10, 2018
Published by admin_auro at August 10, 2018
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Estrogen functions as a longevity promoter: Estrogen, a female steroid hormone, may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 10/August/2018, 10.27 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]
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