Ideas

December 5, 2018
Published by admin_auro at December 5, 2018
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Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced ovarian cancer and other metastatic cancers: A pharmaceutical mixture encompassing Olaparib, an FDA-approved poly (adenosine diphosphate-ribose) polymerase inhibitor, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as KIBRA, p57Kip2,   p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 5/December/2018, 2.29 pm

Introduction: What they say: A study from the Stephenson Cancer Center at the University of Oklahoma, Oklahoma City (K.M.); University of Milan-Bicocca, European Institute of Oncology […]
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December 5, 2018
Published by admin_auro at December 5, 2018
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A probiotic-based therapy for Metastatic cancers: Probiotic Lactobacillus Rhamnosus decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up-regulation of its target gene, 5/December/2017, 2.18 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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December 5, 2018
Published by admin_auro at December 5, 2018
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A probiotic-based immune enhancement therapy: Probiotic Lactobacillus Brevis increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 5/December/2018, 2.02 pm

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
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December 3, 2018
Published by admin_auro at December 3, 2018
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Hot water immersion-based adjuvant therapy for aging-associated diseases and Lifespan extension: Hot water immersion (at 39C for 1 hour) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 3/November/2018, 11.45 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
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